In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Human Goodness: Pragmatic Variations on Platonic ThemesCatherine E. MorrisonHuman Goodness: Pragmatic Variations on Platonic Themes by Paul Schollmeier Cambridge: Cambridge University Press, 2006. Pp. x + 302. $80.00, cloth.This is a book about spirits—human, godly, ghostly, and alcoholic. Paul Schollmeier's Human Goodness: Pragmatic Variations on Platonic Themes explores how humble humans act morally in an absurd world. Schollmeier contends that the Socratic spirit, or daimon, of self-knowledge and (...) hypothesis testing provides the foundation for a deeply human moral philosophy. It is, in Schollmeier's elegant phrasing, daimonic rather than eudaimonic, joining Aristotle and Plato with William James, as well as contributions from the ghosts of David Hume and Immanuel Kant and a few rounds of whiskey. Spirits abound! Mixing Socratic skepticism with Jamesian empiricism, Schollmeier argues that we act best when we apply general principles held as opinion (not as certain knowledge), and tested through experience, to our particular situation. When these opinions yield fruit, we find ourselves less at the whim of our capricious surroundings; when they do not, we are obliged to recognize the provisional nature of our opinions and change them. The ends of these day-to-day activities reflect a far grander cosmological order, one we ignore to our mortal (and moral) peril. It is by engaging in this intellectual activity that we are made happy, and it is in measured pursuit of this happiness that we are virtuous. Our actions are neither absolutely true nor perfect. They are instead the best that we can do. And for a reviewer attempting to encapsulate a finely nuanced book in a small space, this is comforting advice indeed. [End Page 190]The book begins with a puzzle: The curious twin claims in Plato's Apology that, true to the Delphic oracle's proclamation, Socrates is both wise and knows nothing. The key to this apparent paradox, Schollmeier contends, is the difference between divine knowledge, "ultimate, nonhypothetical knowledge of final causes" (6), and human knowledge, which is hypothetical only. Schollmeier marshals William James to argue that as humans, we encounter objects of knowledge perceptually; even our concepts are fashioned from this meager material. Without access to divine knowledge, humans must test hypotheses and assume that they are true only provisionally.James's (and Hume's) emphasis on the passions as the foundation for action, however, gives Schollmeier pause. In order to construct a moral philosophy that avoids absolutism but remains objective, Schollmeier argues for a harmony between the intellectual and the passional that is ultimately rational, our Socratic daimon. We are neither gods nor animals. Should we surrender rationality to desire, Schollmeier warns in concert with Socrates, our already fragile perceptual knowledge will be further distorted by fickle emotion. It is precisely because our grasp on the world is so tenuous that we must pay heed to cool intellect rather than hot passion.Such skepticism of our claim to know might make one hesitant to engage in the enigmatic world—but we have no choice! In order to find our hybrid daimon, both Socratic and pragmatic, Schollmeier suggests rhetoric as the methodology best suited to serving practical knowledge because it eschews certainty in favor of probability and acknowledges that the hypotheses on which we act are tentative and revisable. To this end, Schollmeier highlights the enthymeme and argument by example as the two techniques that best suit the nature of our hypothetical knowledge, and he urges a return to philodoxy, the love of opinion.Giving up our claim to certainty need not be a dismal proposition. Having established his methodology, Schollmeier begins building a moral philosophy that embraces an ontology of change and contends that our happiness provides us with stability in the form of a rational teleology. The objects of our human happiness are fleeting and changeable, so happiness cannot be static but is, rather, an activity that is its own end, "an activity that is an intellectual inquiry" (78). Our happiness is contingent on our ability to hypothetically determine, in our particular setting, our function and then fulfill this role to the best of our abilities. Depending on the setting, it may be dancing, parenting, or simply a lively... (shrink)

Book Review of Michael Gilbert's Arguing with People.

This paper goes beyond — transcends — “pedagogy as justice,” recognizing that justice, particularly in these present times, may not be enough. Its wager is with pedagogies of and for life; pedagogies that plant and cultivate, that push and enable other modes of living, despite the capitalist-modern-colonial-racist system, beyond the system, and in the system's margins, borders, fissures, and cracks. These pedagogies, as Catherine Walsh argues here, are necessarily tied to and constitutive of decolonial(izing) praxis, a praxis that, while (...) not negating justice, takes us beyond it. The argument here is for the pedagogical-praxistical work being done now, and yet to be done; the actional thought, thoughtful action, and ongoing creation and construction of an otherwise for existence, for dignity, and for life in these times of multiple entwined pandemic-viruses, including capitalist greed, systemic racism, heteropatriarchy, and existential-territorial dispossession in which COVID is/was one more thread of the entwine. (shrink)

Researchers now commonly collect biospecimens for genomic analysis together with information from mobile devices and electronic health records. This rich combination of data creates new opportunities for understanding and addressing important health issues, but also intensifies challenges to privacy and confidentiality. Here, we elucidate the “web” of legal protections for precision medicine research by integrating findings from qualitative interviews with structured legal research and applying them to realistic research scenarios involving various privacy threats.

Secreted Frizzled‐related proteins (SFRPs) are modulators of the intermeshing pathways in which signals are transduced by Wnt ligands through Frizzled (Fz) membrane receptors. The Wnt networks influence biological processes ranging from developmental cell fate, cell polarity and adhesion to tumorigenesis and apoptosis. In the five or six years since their discovery, the SFRPs have emerged as dynamically expressed proteins able to bind both Wnts and Fz, with distinctive structural properties in which cysteine‐rich domains from Fz‐ and from netrin‐like proteins are (...) juxtaposed. The abundant expression of SFRP genes in the early embryo, altered expression patterns in disease states, and potential significance in the evolution of the vertebrate body plan, make these intriguing molecules relevant to investigations in diverse fields of biology and biomedical sciences. BioEssays 24:811–820, 2002. © 2002 Wiley Periodicals, Inc. (shrink)

Various promising claims have been made that business can help alleviate poverty, and can do so in ways that add value to the bottom line. This article begins by highlighting that the evidence for such claims is not especially strong, particularly if business is thought of as a development agent, i.e. an organization that consciously and accountably contributes towards pro-poor outcomes. It goes on to ask whether, if we did know more about either the business case or the poverty alleviation (...) case, would this give cause for greater optimism that business could make a significant contribution to development. By exploring the experiences of producers of Fairtrade tea in Kenya, we reveal the complex nature of what constitutes a beneficial outcome for the poor and marginalized, and the gap that can exist between ethical intentions and the experience of their intended beneficiaries. The lessons of these experiences are relevant for Fairtrade and any commercial initiative that seeks to achieve outcomes beneficial and recognizable to the poor, and raise questions about the integration of social and instrumental outcomes that a future generation of ethical entrepreneurship will need to address. (shrink)

Understanding the relationship between obesity and fast food consumption encompasses a broad range of individual level and environmental factors. One theoretical approach, the health capability framework, focuses on the complex set of conditions allowing individuals to be healthy. This qualitative study aimed to identify factors that influence individual level health agency with respect to healthy eating choices in uniformly constrained environments. We used an inductive qualitative research design to develop an interview guide, conduct open-ended interviews with a purposive sample of (...) 14 student fast food workers, and analyze the data. Data analysis was conducted iteratively during the study with multiple coders to identify themes. Emergent themes included environmental influences on eating behaviors and internal psychological factors. A localized, embedded approach to analyzing the factors driving the obesity epidemic is needed. Addressing contextual interactions between internal psychological and external environmental factors responds to social justice and public health concerns, and may yield more relevant and effective interventions for vulnerable communities. (shrink)

The purpose of this article is to understand how historical oppression has undermined health through environmental injustices that have given rise to food insecurity. Specifically, the article examines ways in which settler colonialism has transformed and contaminated the land itself, impacting the availability and quality of food and the overall health of Indigenous peoples. Food security and environmental justice for Gulf Coast, state-recognized tribes has been infrequently explored. These tribes lack federal recognition and have limited access to recourse and supplemental (...) resources as a result. This research fills an important gap in the literature through exploring the intersection of environmental justice and food insecurity issues for this population. Partnering with a community-advisory board and using a qualitative descriptive methodology, 31 Gulf Coast Indigenous women participated in semi-structured interviews about their healthcare experiences and concerns. Through these interviews, participants expressed concerns about (a) the environmental impacts of pollution on the contamination of food and on the health of tribal members; and (b) the impact of these changes on the land, such as negatively impacting gardening practices. The authors of this study document how environmental changes have compounded these concerns and contribute to the overall pollution of food and water sources and unviability of subsistence practices, severely effecting tribal members’ health. In conclusion, we show how social and environmental justice issues such as pollution, industry exploitation, and climate change perpetuate the goals of settler colonialism through undermining cultural practices and the overall health of Indigenous peoples. (shrink)

Machery proposes that the construct of detracts from research progress. However, ignoring development also detracts from research progress. Developmental research has advanced our understanding of how concepts are acquired and thus is essential to a complete theory. We propose a framework that both accounts for development and holds great promise as a new direction for thinking about concepts.

Anorexia nervosa and obsessive–compulsive disorder are commonly reported to co-occur and present with overlapping symptomatology. Executive functioning difficulties have been implicated in both mental health conditions. However, studies directly comparing these functions in AN and OCD are extremely limited. This review provides a synthesis of behavioral and neuroimaging research examining executive functioning in AN and OCD to bridge this gap in knowledge. We outline the similarities and differences in behavioral and neuroimaging findings between AN and OCD, focusing on set shifting, (...) working memory, response inhibition, and response monitoring. This review aims to facilitate understanding of transdiagnostic correlates of executive functioning and highlights important considerations for future research. We also discuss the importance of examining both behavioral and neural markers when studying transdiagnostic correlates of executive functions. (shrink)

In what constitutes the only English-language collection of essays ever dedicated to the analysis of Montesquieu's contributions to political science, the contributors review some of the most vexing controversies that have arisen in the interpretation of Montesquieu's thought. By paying careful attention to the historical, political, and philosophical contexts of Montesquieu's ideas, the contributors provide fresh readings of The Spirit of Laws, clarify the goals and ambitions of its author, and point out the pertinence of his thinking to the problems (...) of our world today. (shrink)

The rapid growth of next-generation genetic sequencing has prompted debate about the responsibilities of researchers toward genetic incidental findings. Assuming there is a duty to disclose significant incidental findings, might there be an obligation for researchers to actively look for these findings? We present an ethical framework for analyzing whether there is a positive duty to look for genetic incidental findings. Using the ancillary care framework as a guide, we identify three main criteria that must be present to give rise (...) to an obligation to look: high benefit to participants, lack of alternative access for participants, and reasonable burden on researchers. Our analysis indicates that there is no obligation to look for incidental findings today, but during the ongoing translation of genomic analysis from research to clinical care, this obligation may arise. (shrink)

Research on children interacting with each other encompasses a wide variety of specific research interest, including but not limited to a focus on language. In this introduction to an issue of Discourse Studies devoted to the contribution of peer talk to pragmatic development, we define ‘peer talk’ as an interdisciplinary field of inquiry and we critically review literature on the role of peer talk in children’s pragmatic development. We suggest that ‘peer talk’ as a field of inquiry properly encompasses studies (...) of the development of language through peer interaction as well as the ways in which peer talk functions in children’s co-construction of their social and cultural worlds. Research reviewed here suggests that peer talk may be a crucial site for pragmatic development, offering children a wide range of opportunities for mutual learning of interactive as well as linguistic skills. The evidence we review, which comes from the fields of language socialization, second language learning, and child-discourse, highlights two major contextual features of peer talk: its collaborative, multi-party, symmetrical participation structure; and its role in the co-constructed worlds of childhood culture. Finally, we call for research and theorizing that would bridge the gap between developmental and ethnographically-informed approaches to the study of child discourse, in order to ensure that children’s peer talk receives the attention due it as a major site for both the development of discourse skills and the creation of childhood culture. (shrink)

This tribute to the breadth and influence of Trudy Govier's philosophical work begins with her early scholarship in argumentation theory, paying special attention to its pedagogical expression. Most people first encounter Trudy Govier's work and many people only encounter it through her textbooks, especially A Practical Study of Argument, published in many editions. In addition to the work on argumentation that has continued throughout her career, much of Govier's later work addresses social philosophy and the problems of trust and response (...) to moral wrongs. The introduction by Catherine Hundleby situates Govier's research along the path of her unusual academic life. While following the timeline of Govier's research publication, in this collection the authors build on her work and suggest certain new connections between her argumentation theory and social philosophy. A Practical Study of Argument, first published in 1985, situates Govier among a distinct segment of informal logicians whose concerns about teaching reasoning to post-secondary students orient their research, Takuzo Konishi argues. Moira Kloster evaluates Govier's progress in the challenge of providing critical thinking education to diverse and changing social contexts. Shifting gears to social philosophy but still addressing education, Laura Elizabeth Pinto explores the significance of Govier's work on trust for explaining the problem of "audit culture" for teaching. At the centre of this volume, social philosophy receives an abstract meta-ethical defense from Linda Radzik. Moving solidly into the domain of normative social philosophy, Alice MacLachlan reconsiders Govier's condemnation of revenge by viewing it as a form of moral address, but she notes how revenge as an act of communication contrasts with argumentation in lacking the respect that Govier maintains is intrinsic to argumentation. MacLachlan ultimately agrees that revenge is morally indefensible. The practical challenges of addressing others in the aftermath of wrongdoing, especially in public contexts, can make it difficult to distinguish between victims and combatants or wrongdoers, Alistair Little and Wilhelm Verwoerd explain, and Kathryn Norlock argues that forgiveness is psychologically vexed too. People may recognize transformation to be in principle possible for all people, Norlock argues, and yet we may find the evidence regarding some particular evildoer sufficient to count that person as an exception. Finally Govier responds to the various papers. (shrink)

Sanford Goldberg’s account of epistemic coverage constitutes a special case of Douglas Walton’s view that epistemic closure arises from dialectical argument. Walton’s pragmatic version of epistemic closure depends on dialectical norms for closing an argument, and epistemic coverage operates at the limits of argument closure because it minimizes dialectical exchange. Such closure works together with a shared hypothetical consideration to justify dismissal of surprising claims.

This project explored what constitutes “ethical practice of mathematics”. Thematic analysis of ethical practice standards from mathematics-adjacent disciplines (statistics and computing), were combined with two organizational codes of conduct and community input resulting in over 100 items. These analyses identified 29 of the 52 items in the 2018 American Statistical Association Ethical Guidelines for Statistical Practice, and 15 of the 24 additional (unique) items from the 2018 Association of Computing Machinery Code of Ethics for inclusion. Three of the 29 items (...) synthesized from the 2019 American Mathematical Society Code of Ethics, and zero of the Mathematical Association of America Code of Ethics, were identified as reflective of “ethical mathematical practice” beyond items already identified from the other two codes. The community contributed six unique items. Item stems were standardized to, “The ethical mathematics practitioner…”. Invitations to complete the 30-min online survey were shared nationally (US) via Mathematics organization listservs and other widespread emails and announcements. We received 142 individual responses to the national survey, 75% of whom endorsed 41/52 items, with 90–100% endorsing 20/52 items on the survey. Items from different sources were endorsed at both high and low rates. A final thematic analysis yielded 44 items, grouped into “General” (12 items), “Profession” (10 items) and “Scholarship” (11 items). Moreover, for the practitioner in a leader/mentor/supervisor/instructor role, there are an additional 11 items (4 General/7 Professional). These results suggest that the community perceives a much wider range of behaviors by mathematicians to be subject to ethical practice standards than had been previously included in professional organization codes. The results provide evidence against the argument that mathematics practitioners engaged in “pure” or “theoretical” work have minimal, small, or no ethical obligations. (shrink)

Is morality real? Yale University ethicist Shelly Kagan thinks that it is: he aims to prove so in his recent book. By outlining a variety of skeptical positions and providing rebuttals to each one,...

Moira Kloster suggests the frailty of argument across differences in circumstances of disagreement. My aim is to take a step back and consider what she takes to be the purpose of argumentative bridges. I explain my understanding of Kloster’s position that we must attend to the variable places that cooperation and trust have in argumentation, especially how these attitudes are sometimes institutionalized in such a way that a cooperative individual disposition becomes dysfunctional. Kloster’s considerations are quite sound for arguments in (...) the institutional contexts that concern her; her observation about the dependence of an argument’s value on the purpose of its institutional context is considered in light of further purposes that argumentation serves inside and outside of institutions. I agree that we need to consider how social contexts and institutions affect the various successes of argumentation, but I think we need to consider also the range of purposes that arguments and argument forums may have, what values they may support, and what interests they may serve. (shrink)

Despite the burgeoning literature on professionalism in other health professions, psychology lags behind in the level of attention given to this core competency. In this article, we review definitions from other health professions and how they address professionalism. Next, we review how this competency evolved within health service psychology (HSP), and we propose a definition. We offer an approach for assessing professionalism within HSP. Consideration is given to strategies and methods for providing effective education and training in this multifaceted competency. (...) Finally, recommendations are made for creating a culture of professionalism within HSP and honoring psychology’s social contract with multiple publics. (shrink)

Eduardo Frei Montalva, co-founder of the Christian Democratic Party and President of Chile, represented for Jacques Maritain, French neo-Thomist philosopher, an example of prophetic leadership in contemporary times. According to Maritain, modem democracy could not survive without a profound spiritual revolution of political leadership--the "prophetic factor" of democracy--which he observed in Frei as a public official, senator, and ultimately the Presient of the Republic of Chile (1964-1970). Under his famed "Revolution in Liberty," Frei endeavored to meld socio-economic reforms with an (...) effort to build a more participatory democratic culture in his native land. Guided by Maritain's political philosophy, Frei's initiatives set into motion the possibility of a "third way" of politics in the Southern hemisphere. In the end, this revolution ended in political disappointment due to economic stagnation, social disruption, political infighting, and the impractical idealism of Christian democracy itself. (shrink)

Conducted among parents of young ice hockey players, this field experiment tested if making salient increasingly popular social norms that promote sportspersonship, learning, and having fun in sports, increases parents’ own self-determined endorsement of these behaviors and values, improves their psychological well-being, and impacts on their children’s on-ice behaviors. Hockey parents were randomly assigned to the experimental condition vs. control condition. Parents’ motivations for encouraging their child to learn and to have fun in hockey were then assessed. Score sheets for (...) the games that followed the study provided access to their children’s on-ice behaviors, as indicators of sportspersonship. Parents in the experimental condition reported higher self-determination for encouraging their child to learn and have fun in hockey compared to parents in the control condition. Furthermore, children of parents in the experimental condition had more assists. A mediation model revealed that the dynamic norms manipulation increased parents’ self-determined motivation for encouraging their child to learn and to have fun in hockey, which in turn, predicted higher psychological well-being. Together, these results provide support for the contention that highlighting increasingly popular social norms that promote sportspersonship, learning, and fun in sports, represents a promising strategy for creating positive social change in this life context. (shrink)

Can the 1985 proposal for the unification of the Christian churches co-authored by Karl Rahner and Heinrich Fries in Unity of the Churches: An Actual Possibility still provide a realistic basis for the unification of the churches? This paper considers the proposal as an application of the ecumenical principle that no greater burden than necessary be imposed as a requisite for full ecclesial communion, and of the hierarchy of truths. It explores the basic presuppositions of the proposal in light of (...) Rahner’s reflections on the role of the creed within the context of theological pluralism. Finally, it considers the changing contours of global Christianity and the potential of Rahner’s thought to hold together in creative tension the at times competing currents of those who would locate the ultimate basis of unity in a maximalist theological orthodoxy and those who would find it in an almost exclusive emphasis on orthopraxy. (shrink)

Feminists note an association of arguing with aggression and masculinity and question the necessity of this connection. Arguing also seems to some to identify a central method of philosophical reasoning, and gendered assumptions and standards would pose problems for the discipline. Can feminine modes of reasoning provide an alternative or supplement? Can overarching epistemological standards account for the benefits of different approaches to arguing? These are some of the prospects for argumentation inside and outside of philosophy that feminists consider. -/- (...) The further concern is that the academic study of argumentation – in philosophy and other disciplines – has failed to account for the type of reasoning needed for social justice movements. What resources for addressing these concerns can be found in informal logic and interdisciplinary argumentation theory? Since part of the perceived problem derives from assuming that arguing is a contest, are more collaborative epistemological frameworks better? Can regular politeness or civility hedge against undesirable tendencies of argumentation? Can “critical thinking” pedagogy involving argument educations answer the needs of social justice? (shrink)

Across disciplines there is a large and increasing number of research projects that rely on data collection activities in low- and middle-income countries (LMICs). However, these are accompanied by an extensive range of ethical challenges. While the safeguarding of study participants is the primary aim of existing ethics guidelines, this paper argues that this “do no harm” principle should be extended to include research staff. This study is a comprehensive review of more than 80 existing ethics guidelines and protocols that (...) reveals a lack of safeguarding research staff regarding the ethical challenges faced during data collection activities in LMICs. This is particularly the case when it comes to issues such as power imbalances, political risk, staff’s emotional wellbeing or dealing with feelings of guilt. Lead organizations are called upon to develop guiding principles that encompass the safeguarding of research staff, which are then to be adapted and translated into specific protocols and tools by institutions. (shrink)

The protection of employee rights in the workplace is one of the fundamental ethical questions facing organizations today. Organizations differ in the extent to which they protect the rights of both employees and themselves as employers, yet little research has examined the types of organizations that have rights protection policies. Instead of the classic normative approach to ethical issues, this study took a contextual approach to the management of rights in the workplace through human resource policies. Associations were found between (...) the organizational characteristics of size, industry, unionization, business condition, and the existence of employee and employer rights policies. Additional analyses revealed underlying dimensions in right policies and the relationship of organizational characteristics to these aspects of rights management were examined. The results are discussed in terms of understanding human resource rights management within an organizational context. (shrink)

Recent work in feminist and postcolonial rhetoric demonstrates various meanings of silence. Listening rhetorically in order to comprehend silences is particularly difficult in scientific contexts, I argue, because the common ground for scientific discourse assumes a culture of disclosure. Rhetorical listening is also important to science because listening accounts for silence as well as disclosure, and so maximizes the diversity in recognized perspectives that provides scientific objectivity.

Three experiments demonstrated that decisions resulting in considerable amounts of profit, but missed alternative outcomes of greater profits, were rated lower in quality and produced more regret than did decisions that returned lesser amounts of profit but either did not miss or missed only slightly better alternatives. These effects were mediated by upward counterfactuals and moderated by participants’ orientation to the decision context. That decision evaluations were affected by the availability and magnitude of alternative outcomes rather than the positivity of (...) actual outcomes is counter to the outcome bias effect—a bias in which decisions are rated more positively when they led to more positive outcomes. Experiment 3 demonstrated that these effects represent a bias that occurs even when it is clear that the process by which decisions were made followed rational decision processes. This research suggests that when alter.. (shrink)

I will situate the fallacies approach to reasoning with the aim of making it more relevant to contemporary life and thus intellectually significant and valuable as a method for teaching reasoning. This entails a revision that will relegate some of the traditional fallacies to the realm of history and introduce more recently recognized problems in reasoning. Some newly recognized problems that demand attention are revealed by contemporary science studies, which reveal at least two tenacious problems in reasoning that I will (...) explore in this paper. One of these problems is androcentrism, a ubiquitous problem with reasoning that feminists exposed in the twentieth century but that continues to pervade people’s reasoning. The other is biological reductionism in at least two specific forms: genetic determinism and adaptationism. (shrink)

Three major strategies exist for the protection of endangered habitat and species: (1) land acquisition programs, (2) government legislation and regulatory agencies, and (3) "stewardship" programs that are voluntary and community-based. While all of these strategies have merit, we suggest that stewardship holds particular advantages and should be considered more often as a strategy of first choice. In this article, we examine the Municipal Wetland Stewardship program of Newfoundland, a popular and successful Canadian policy for the local protection of wetlands. (...) Important issues are at stake: competing philosophical foundations for managerial ecology, the value of "local ecological knowledge," principles of community-based conservation, the question of whether stewardship empowers local communities or controls them from afar, and ethical conflicts around American colonialism, hunting, and ecotourism. The results suggest that despite some potentially problematic ironies, the Newfoundland program provides a model for a public policy aimed both at the pragmatics of biophysical sustainability and at the ideals of environmental ethics, social justice, and democratic politics. (shrink)

Background: Clinical investigation is a growing field employing increasing numbers of nurses. This has created a new specialty practice defined by aspects unique to nursing in a clinical research context: the objectives (to implement research protocols and advance science), setting (research facilities), and nature of the nurse–participant relationship. The clinical research nurse role may give rise to feelings of ethical conflict between aspects of protocol implementation and the duty of patient advocacy, a primary nursing responsibility. Little is known about whether (...) research nurses experience unique ethical challenges distinct from those experienced by nurses in traditional patient-care settings. Research objectives: The purpose of the study was to describe the nature of ethical challenges experienced by clinical research nurses within the context of their practice. Research design: The study utilized a qualitative descriptive design with individual interviews. Participants and research context: Participating nurses (N = 12) self-identified as having experienced ethical challenges during screening. The majority were Caucasian (90%), female (83%), and worked in outpatient settings (67%). Approximately 50% had > 10 years of research experience. Ethical considerations: The human subjects review board approved the study. Written informed consent was obtained. Findings: Predominant themes were revealed: (1) the inability to provide a probable good, or/do no harm, and (2) dual obligations (identity as a nurse vs a research nurse). The following patterns and subthemes emerged: conflicted allegiances between protocol implementation, needs of the participant, desire to advance science, and tension between the nurse–patient therapeutic relationship versus the research relationship. Discussion: Participants described ethical challenges specific to the research role. The issues are central to the nurse–participant relationship, patient advocacy, the nurse’s role in implementing protocols, and/or advancing science. Conclusion: Ethical challenges related to the specialized role of clinical research nurses were identified. More research is warranted to fully understand their nature and frequency and to identify support systems for resolution. (shrink)